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Wei-Shou Hu

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Wei-Shou Hu
Born (1951-11-05) November 5, 1951 (age 72)
Taiwan
NationalityTaiwanese
CitizenshipUnited States
Alma materNational Taiwan University (BS)
Massachusetts Institute of Technology (PhD)
Known forCell culture engineering
Scientific career
FieldsChemical engineering
Biochemical engineering
InstitutionsUniversity of Minnesota
Doctoral advisorDaniel Wang

Wei-Shou Hu (born November 5, 1951) is a Taiwanese-American chemical engineer. He is currently the Distinguished McKnight University Professor of Chemical Engineering and Material Science at the University of Minnesota.

Education

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He earned his B.S. in agricultural chemistry from National Taiwan University in 1974 and his Ph.D. in biochemical engineering from the Massachusetts Institute of Technology under the guidance of Daniel I.C. Wang in 1983. He has been a professor with the University of Minnesota since 1983. Hu has long impacted the field of cell culture bioprocessing since its infancy by steadfastly introducing quantitative and systematic analysis into this field. His work, which covers areas such as modeling and controlling cell metabolism, modulating glycosylation, and process data mining, has helped shape the advances of biopharmaceutical process technology. He recently led an industrial consortium to embark on genomic research on Chinese hamster ovary cells, the main workhorse of biomanufacturing, and to promote post-genomic research in cell bioprocessing.[1]

Hu's research focuses on the field of cell culture bioprocessing, particularly metabolic control of the physiological state of the cell.[2][3] In addition to his work with Chinese hamster ovary cells, his work has enabled the use of process engineering for cell therapy, especially with liver cells.[4][5] Hu has written four different biotechnology books.[6][7][8][9] One of his articles is cited by 63.[10]

He is the 2005 recipient of the Marvin Johnson Award from the American Chemical Society, the distinguished service award of Society of Biological Engineers, a special award from Asia Pacific Biochemical Engineering Conference (2009), and the Amgen Award from Engineering Conferences International, as well as both the distinguished service award and the Division award from the Food, Pharmaceuticals and Bioengineering Division of the American Institute of Chemical Engineers.[1] He has authored the books Bioseparations, Cell Culture Technology for Pharmaceutical and Cell-Based Therapies and Cell Culture Bioprocess Engineering

References

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  1. ^ a b "2015 Amgen Biochemical Engineering Award to Dr. Wei-Shou Hu" (PDF). Engineering Conferences International. Retrieved 29 June 2015.
  2. ^ Hu, Wei-Shou; Dodge, Timothy C. (December 1985). "Cultivation of Mammalian Cells in Bioreactors". Biotechnology Progress. 1 (4): 209–215. doi:10.1002/btpr.5420010404. PMID 20568168. S2CID 12916459.
  3. ^ "Dr. Wei-Shou Hu". AICHE. 29 February 2012. Retrieved 29 June 2015.
  4. ^ Nyberg, SL; Remmel, RP; Mann, HJ; Peshwa, MV; Hu, WS; Cerra, FB (July 1994). "Primary hepatocytes outperform Hep G2 cells as the source of biotransformation functions in a bioartificial liver". Annals of Surgery. 220 (1): 59–67. PMC 1234288. PMID 8024360.
  5. ^ Schwartz, RE; Reyes, M; Koodie, L; Jiang, Y; Blackstad, M; Lund, T; Lenvik, T; Johnson, S; Hu, WS; Verfaillie, CM (May 2002). "Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells". The Journal of Clinical Investigation. 109 (10): 1291–302. doi:10.1172/jci15182. PMC 150983. PMID 12021244.
  6. ^ Hu, Wei-Shou (2020). Cell culture bioprocess engineering (Second ed.). Boca Raton, FL. ISBN 978-1498762854.{{cite book}}: CS1 maint: location missing publisher (link)
  7. ^ Hu, Wei-Shou (2017). Engineering principles in biotechnology. Newark: Wiley. ISBN 978-1-119-15902-5.
  8. ^ Hu, Wei-Shou (2012). Cell culture bioprocess engineering. [Minnesota]. ISBN 978-0985662608.{{cite book}}: CS1 maint: location missing publisher (link)
  9. ^ Hu, Wei-Shou (2012). Genomics and systems biology of mammalian cell culture. Berlin. ISBN 978-3642434068.{{cite book}}: CS1 maint: location missing publisher (link)
  10. ^ Hu, Wei-Shou (2007). "Comparative genomic hybridizations reveal absence of large Streptomyces colicolor genomic islands in Streptomyces lividans". BMC Genomics. 8: 229-241. doi:10.1186/1471-2164-8-229. PMC 1934918. PMID 17623098.
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